The new US president, Joe Biden, has signaled his commitment to resetting the US relationship with countries in Africa, including through a focus on fighting corruption and advancing human rights on the national and regional level. As part of this commitment to promoting democracy and enhancing protections for historically marginalised groups, the Biden administration should double down on a human rights-centred policy in Sudan. There is real momentum in Sudan for important reforms, but strong voices for change must contend with a deepening economic crisis and political headwinds. Recognising these challenges, the US should take concrete action to reinforce recent steps towards democratization and human rights reforms. This Briefing Note by REDRESS and PLACE lays out several human rights priorities for the United States in Sudan under the new administration.